RESUMEN
The objective of this study was to investigatebone response after implantation of MTA (MineralTrioxide Aggregate) in the rabbit mandible.Experiments were carried out on the rightmandibular body of 8 adult male rabbits. Theanimals were divided into two groups (controlgroup and test group). In this in vivo study, MTAwas used as an interpositional graft material incritical-size bone defects of rabbit mandibles.The animals were sacrificed on day 30 after surgery.The samples obtained from the mandibleswere subjected to histological procedures, whichpermitted the collection of sections with a thicknessof 60±10ìm. The sections were stained withHaematoxylin and Eosin and Goldner Trichromestain and examined under a light microscope.No important inflammatory reactions weredetected in any of the samples of the treatedgroup. The results confirm the excellent biocompatibilityof MTA. The implantation of MTA inbone defects led to bone regeneration 4 weeksafter surgery. However, the growth rate was notsignificant and the amount of newly formed bonewas limited with the use of MTA in this specificapplication. Sample examination did not suggestcomplete evidence of new bone growth from eitheran inductive or conductive perspective.The objective of this study was to investigatebone response after implantation of MTA (MineralTrioxide Aggregate) in the rabbit mandible.Experiments were carried out on the rightmandibular body of 8 adult male rabbits. Theanimals were divided into two groups (controlgroup and test group). In this in vivo study, MTAwas used as an interpositional graft material incritical-size bone defects of rabbit mandibles.The animals were sacrificed on day 30 after surgery.The samples obtained from the mandibleswere subjected to histological procedures, whichpermitted the collection of sections with a thicknessof 60+-10microm. The sections were stained withHaematoxylin and Eosin and Goldner Trichromestain and examined under a light microscope.No important inflammatory reactions weredetected in any of the samples of the treatedgroup. The results confirm the excellent biocompatibilityof MTA. The implantation of MTA inbone defects led to bone regeneration 4 weeksafter surgery. However, the growth rate was notsignificant and the amount of newly formed bonewas limited with the use of MTA in this specificapplication. Sample examination did not suggestcomplete evidence of new bone growth from eitheran inductive or conductive perspective
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